Grape seed extract is a dietary supplement available as liquid, tablets, or capsules. it is rich in antioxidants and may help to heal wounds, strengthen bones, prevent skin cancer, and fight. The grape seeds used to produce grape seed extract are generally obtained from wine manufacturers." opcs help make grape seed extract a health superstar. one of grape seed extract's claims to fame is opcs, which are related to the much more well-known compound resveratrol (found in grape skins).. Grape seed extract and proanthocyanidins have been marketed in france for decades as treatment for venous and capillary disorders, and the extract is used extensively in japan as a food additive and antioxidant. cold-pressed grape-seed oil, obtained as a by-product of wine making, is used in cooking and salad dressings.2, 3, 4. chemistry.